Fig. 5

Cancer type classification accuracy of the expanded TCGA/GSE validation cohort (n = 5923). A Sample number and prediction accuracy (%) of each cancer type. B Sensitivity, specificity, PPV, and NPV for each of the 25 cancer types. C Confusion matrix (in percent) of the expanded TCGA/GSE validation cohort of cancer type prediction using 200 selected probes. The percentages of correctly predicted samples are highlighted in green; misclassification events are highlighted in pink. True histology/predicted histology is respectively listed in rows/columns. ACC Adrenocortical carcinoma, BLCA Bladder urothelial carcinoma, BRCA Breast invasive carcinoma, CESC Cervical squamous cell carcinoma and endocervical adenocarcinoma; CRC Colorectal cancer, HLM Hematolymphoid malignancies, HN/ESCC Head and neck squamous carcinoma and esophageal squamous cell carcinoma, LIHC Liver hepatocellular carcinoma, LUAD Lung adenocarcinoma, LUSC Lung squamous cell carcinoma, MESO Mesothelioma, PAAD Pancreatic adenocarcinoma, PCPG Pheochromocytoma and paraganglioma, PRAD Prostate adenocarcinoma, SARC Sarcoma, SKCM Skin cutaneous melanoma, TGCT Testicular germ cell tumors, THCA Thyroid carcinoma, THYM Thymoma, UC Uterine cancer, Upper GI Upper gastrointestinal adenocarcinoma, UVM Uveal melanoma