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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Identification of DNA methylation biomarkers for evaluating cardiovascular disease risk from epigenome profiles altered by low-dose ionizing radiation

Fig. 5

Bisulfite sequencing analysis of CpG islands in the promoter regions of the candidate genes. Bisulfite sequencing analysis was performed with irradiated HAECs. The location of CpG sites in the PGRMC1 (upstream region from − 415 to − 196) relative to the TSSs of exon 1 are UNC119B (upstream region from − 422 to − 186), FNDC3B (upstream region from − 126 to + 36), and RERE (upstream region from + 239 to + 494), where each box represents a CpG dinucleotide. Black boxes represent methylated cytosines, and white boxes represent unmethylated cytosines

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Clinical Epigenetics

ISSN: 1868-7083

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