Table 1 Clinical characteristics of the training cohort
Characteristic | Controls, N = 10a | ICUS, N = 65a | CCUS, N = 39a | MDS, N = 57a | p valueb |
|---|---|---|---|---|---|
Age | 59.0 (24.0, 66.0) | 66.0 (17.0, 89.0) | 70.0 (50.0, 89.0) | 74.0 (26.0, 96.0) | < 0.001 |
Sex | 0.272 | ||||
Female | 6 (60%) | 23 (35%) | 13 (33%) | 16 (28%) | |
Male | 4 (40%) | 42 (65%) | 26 (67%) | 41 (72%) | |
Hgb | 8.0 (4.5, 10.4) | 6.7 (4.5, 8.7) | 6.2 (4.8, 14.0) | < 0.001 | |
Missing | 0 | 0 | 9 | ||
ANC | 2.1 (0.3, 7.8) | 2.0 (0.6, 8.0) | 1.4 (0.3, 11.4) | 0.007 | |
Missing | 2 | 0 | 11 | ||
Platelets | 126.0 (22.0, 417.0) | 113.0 (18.0, 427.0) | 115.0 (6.0, 666.0) | 0.477 | |
Missing | 1 | 0 | 8 | ||
IPSS-R category | > 0.999 | ||||
Very low | 3 (6.4%) | ||||
Low | 23 (49%) | ||||
Intermediate | 10 (21%) | ||||
High | 7 (15%) | ||||
Very high | 4 (8.5%) | ||||
Missing | 10 | ||||
No. of mutations | |||||
0 | 54 (100%) | 2 (5.1%) | 3 (15%) | ||
1 | 0 (0%) | 18 (46%) | 6 (30%) | ||
2 | 0 (0%) | 15 (38%) | 5 (25%) | ||
3 | 0 (0%) | 2 (5.1%) | 5 (25%) | ||
4 | 0 (0%) | 2 (5.1%) | 1 (5.0%) | ||
Missing | 11 | 0 | 37 |