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Fig. 5 | Clinical Epigenetics

Fig. 5

From: DNA methylation age in paired tumor and adjacent normal breast tissue in Chinese women with breast cancer

Fig. 5Fig. 5

DNAm age acceleration and aging markers in normal and tumor tissue. Correlations between DNAm age acceleration in tumor tissue and single-base substitution (SBS) COSMIC mutational signatures A SBS 1; B SBS 5; C Association between DNAm age acceleration and telomere length (estimated using WGS data) stratified by tissue type; D Association between DNAm age acceleration and CDKN2A gene expression; E Distribution of CDKN2A gene expression in normal and tumor tissue. Pearson correlation test was utilized to test for significance of the correlation between each marker and DNAm age acceleration, separately

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Clinical Epigenetics

ISSN: 1868-7083

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