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Table 1 Patient demographics

From: A phase 1 clinical trial of the repurposable acetyllysine mimetic, n-methyl-2-pyrrolidone (NMP), in relapsed or refractory multiple myeloma

Characteristic

Patients (n = 13)

Age, median [range]

73 [54–85]

Gender, n (%)

 Male

8 (62)

 Female

5 (38)

ECOG performance status, n (%)

 0

7 (54)

 1

6 (46)

Prior lines of therapy, n (%)

 2

4 (31)

 3

1 (8)

  > 3

8 (62)

Median prior lines [range]

4 [2–9]

Response to prior therapy, n (%)

 Refractory

6 (46)

 Relapsed

4 (31)

 Intolerant

3 (23)

Laboratory parameters, median [range]

 Creatinine clearance (mL/min)

84 [41–176]

 β2 microglobulin (mg/L)

4.7 [2.0–13.6]

 Albumin (g/L)

35 [29–45]

 Paraprotein (g/L)

15 [0–52]

 Kappa FLC (mg/L)

154 [5.2–1764]

 Lambda FLC (mg/L)

5.8 [0.4–314]

  1. FLC free light chains