Fig. 1
From: Longitudinal associations of DNA methylation and sleep in children: a meta-analysis
Newborn DNAm at birth and parent-reported child sleep duration among 3658 school-aged children. A Manhattan plota. B Quantile–quantile plot (λ = 1.01)b. aPanel A is a Manhattan plot: the x-axis shows the location of the CpG site in the genome, and the y-axis shows the − log10(p) of the observed meta-analytical association between DNAm at this CpG at birth and parent-rated sleep duration in childhood. The red line corresponds to the cut-off of statistical significance after multiple testing correction (4.0 × 10–8). bPanel B is a quantile–quantile plot that shows the distribution of observed p values, compared to the distribution expected by chance