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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Age-, tumor-, and metastatic tissue-associated DNA hypermethylation of a T-box brain 1 locus in human kidney tissue

Fig. 1

Genomic organization of the TBR1 gene on chromosome 2 showing two transcripts: exons and genomic regions corresponding to the 5′- and 3′UTRs of TBR1 mRNA are presented with thick and thinner boxes, respectively, distribution of CpG islands (CGI), putative target binding sites of microRNAs on corresponding TBR1 mRNA, location of candidate CpG sites (C and cg:), and location of the pyrosequencing assay (Assay) are shown. Numbers refer to the candidate CpG sites cg05301866 (1), cg06942701 (2), cg06488443 (3), and cg12757011 (4)

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