Fig. 1
From: A new nucleosomic-based model to identify and diagnose SSc-ILD
Individual biomarkers in the blood of SSc compared to SSc-ILD at baseline. Boxplot expressing medians and IQ range for each biomarker in function of diagnosis at T1. The box plots showed significantly higher levels for H3.1 containing cf-nucleosomes (a) and MMP-9 (b) in patients with SSc-ILD (n = 31) compared with SSc patients (n = 67) (p < 0.05 for both), in contrast IGFBP-1 (c) was significantly lower level in patient with SSc-ILD (p < 0.001). P values were determined by Mann-Whitney rank-sum test. The box plot shows the median and the 25th and 75th percentiles; the whiskers indicate 1.5 times the interquartile range (IQR)