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Table 2 Comparison of wd-scores (the integrated model) of risk factors and prognosis associated with pancreatic cancer (n = 61)

From: Integrated epigenetic biomarkers in circulating cell-free DNA as a robust classifier for pancreatic cancer

Variable

Variable level

Wd-score

P value

Age

≥ 60

− 3.894 ± 0.257

0.383

< 60

− 4.2126 ± 0254

Gender

Male

− 3.895 ± 0.230

0.355

Female

− 4.235 ± 0.289

Smoking history

Yes

− 4.079 ± 0.375

0.911

No

− 4.032 ± 0.206

Alcohol history

Yes

− 4.100 ± 0.314

0.831

No

− 4.017 ± 0.224

Chronic disease

Hypertension

Yes

− 4.094 ± 0.372

0.911

No

− 4.038 ± 0.201

 

Type II diabetes

Yes

− 3.622 ± 0.235

0.118

No

− 4.139 ± 0.213

 

CA199, U/mL

> 37

− 3.915 ± 0.200

0.336

< 37

− 4.529 ± 0.401

 

Jaundice

Yes

− 3.000 ± 0.451

0.006

No

− 4.357 ± 0.170

 

Tumor size

< 3 cm

− 3.751 ± 0.198

0.019

> 3 cm

− 4.875 ± 0.337

 

Primary cancer site

Head

− 4.204 ± 0.252

0.439

Tail

− 3.920 ± 0.256

 

Tumor differentiation

High

/

0.721

Moderate

− 4.013 ± 0.337

 

Low

− 4.056 ± 0.215

 

Metastasis

Yes

− 3.929 ± 0.3508

0.9148

No

− 4.087 ± 0.2127

 
  1. wd-score weighted diagnosis score, CA199 carbohydrate antigen199
  2. Note: P values were calculated using t test