From: Newborn and childhood differential DNA methylation and liver fat in school-age children
 | Newborns participants | Non-participants | P value | Children participants | Non-participants | P value |
---|---|---|---|---|---|---|
(n = 785) | (n = 604) | (n = 344) | (n = 120) | |||
Maternal characteristics | Â | Â | Â | Â | Â | Â |
Age, mean (SD), years | 32.1 ± 4.0 | 31.3 ± 4.5 | <0.01 | 32.1 ± 4.0 | 32.5 ± 4.1 | 0.41 |
Prepregnancy body mass index, mean (SD), kg/m2 | 23.2 ± 3.9 | 23.2 ± 3.8 | 0.95 | 23.4 ± 4.0 | 22.7 ± 3.2 | 0.12 |
Parity, n (%), nulliparous | 477 (60.8%) | 365 (60.6%) | 0.96 | 205 (59.6%) | 73 (61.3%) | 0.74 |
Education, n (%), higher education | 535 (68.2%) | 357 (61.1%) | <0.01 | 232 (67.4%) | 75 (65.2%) | 0.86 |
Smoking during pregnancy, n (%), continued | 94 (12.0%) | 88 (18.0%) | <0.01 | 43 (12.5%) | 8 (9.3%) | 0.70 |
Child characteristics | Â | Â | Â | Â | Â | Â |
Gestational age at birth, median (95%), weeks | 40.4 (37.0–42.3) | 40.3 (36.3 – 42.4) | 0.45 | 40.3 (36.9 – 42.4) | 40.4 (37.6–42.4) | 0.63 |
Age, mean (SD), years | NA | NA | NA | 9.8 ± 0.3 | 9.7 ± 0.3 | <0.01 |
Males, n (%) | 378 (48.2%) | 325 (53.8%) | 0.04 | 170 (49.4%) | 61 (50.8%) | 0.79 |
Birth weight, mean (SD), g | 3556 ± 505 | 3528 ± 518 | 0.31 | 3578 ± 515 | 3547 ± 498 | 0.57 |
Body mass index, mean (SD), kg/m2 | 17.0 ± 2.1 | 17.0 ± 2.1 | 0.77 | 17.1 ± 2.0 | 17.2 ± 2.2 | 0.62 |
Children with | Â | Â | Â | Â | Â | Â |
 Underweight, n (%) | 62 (7.9) | 30 (8.1) | 0.12 | 19 (5.5) | 8 (6.7) | 0.21 |
 Normal weight, n (%) | 637 (81.1) | 299 (80.6) | 0.05 | 287 (83.4) | 97 (80.8) | 0.42 |
 Overweight, n (%) | 79 (10.1) | 38 (6.3) | 0.01 | 37 (10.8) | 13 (10.8) | 0.52 |
 Obesity, n (%) | 7 (0.9) | 4 (0.7) | 0.09 | 1 (0.3) | 2 (1.7) | 0.11 |