From: Newborn and childhood differential DNA methylation and liver fat in school-age children
 | Newborns | Childhood |
---|---|---|
(n = 785) | (n = 344) | |
Maternal characteristics | Â | Â |
Age, mean (SD), years | 32.1 ± 4.0 | 32.1 ± 4.0 |
Prepregnancy body mass index, mean (SD), kg/m2 | 23.2 ± 3.9 | 23.4 ± 4.0 |
Parity, n (%), nulliparous | 477 (60.8%) | 205 (59.6%) |
Education, n (%), higher education | 535 (68.2%) | 232 (67.4%) |
Smoking during pregnancy, n (%), continued | 94 (12.0%) | 43 (12.5%) |
Child characteristics | Â | Â |
Gestational age at birth, median (95%), weeks | 40.4 (37.0–42.3) | 40.3 (36.9–42.4) |
Age, mean (SD), years | 0 | 9.8 ± 0.3 |
Males, n (%) | 378 (48.2%) | 170 (49.4%) |
Birth weight, mean (SD), g | 3556 ± 505 | 3578 ± 515 |
Body mass index at 10 years, mean (SD), kg/m2 | 17.0 ± 2.1 | 17.1 ± 2.0 |
Children with | Â | Â |
 Underweight, n (%) | 62 (7.9) | 19 (5.5) |
 Normal weight, n (%) | 637 (81.1) | 287 (83.4) |
 Overweight, n (%) | 79 (10.1) | 37 (10.8) |
 Obesity, n (%) | 7 (0.9) | 1 (0.3) |
Liver fat fraction, median (95% range), % | 2.0 (1.3–4.6) | 2.0 (1.3–5.1) |
Prevalence non-alcoholic fatty liver disease, n (%) | 17 (2.2%) | 9 (2.6%) |