From: Obesity-induced nucleosome release predicts poor cardio-metabolic health
Characteristics | Normal weight (n = 40) | Overweight (n = 40) | Obese (n = 40) | p value |
---|---|---|---|---|
Age, years | 44.0 (16.0) | 48.0 (19.5) | 49.0 (16.0) | 0.393 |
Sex (% male) | 54.3% | 44.1% | 50.0% | 0.664 |
Waist circumference, cm | 75.0 (14.0) | 88.5 (11.0) | 107.0 (15.0) | < 0.001 |
Hip circumference, cm | 94.0 (5.0) | 103.0 (5.0) | 115.0 (12.0) | < 0.001 |
WHR | 0.79 (0.13) | 0.86 (0.12) | 0.94 (0.10) | < 0.001 |
Body fat mass, % | 19.0 (10.0) | 25.9 (13.0) | 38.1 (14.6) | < 0.001 |
Systolic blood pressure, mm Hg | 112.5 (12.0) | 119.8 (19.1) | 125.0 (18.5) | < 0.001 |
Diastolic blood pressure, mm Hg | 76.5 (11.5) | 81.0 (12.3) | 83.5 (10.0) | < 0.001 |
Total cholesterol, nmol/L | 5.3 (1.7) | 5.8 (1.3) | 4.8 (1.2) | 0.011 |
HDL cholesterol, nmol/L | 1.6 (0.5) | 1.4 (0.4) | 1.2 (0.4) | < 0.001 |
LDL cholesterol, nmol/L | 2.9 (1.4) | 3.7 (1.5) | 2.9 (1.0) | 0.006 |
Triglycerides, nmol/L | 0.8 (0.8) | 1.2 (0.5) | 1.5 (1.0) | < 0.001 |
Glucose, nmol/L | 4.7 (0.70) | 5.0 (0.7) | 5.2 (0.8) | < 0.001 |
AST, U/L | 3.9 (0.7) | 3.9 (2.2) | 4.3 (1.9) | 0.388 |
ALT, U/L | 3.6 (1.3) | 4.3 (2.4) | 5.3 (3.5) | < 0.001 |
GGT, U/L | 2.8 (3.1) | 3.3 (2.5) | 5.1 (6.3) | 0.002 |