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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Perturbations in imprinted methylation from assisted reproductive technologies but not advanced maternal age in mouse preimplantation embryos

Fig. 3

Advanced maternal age did not perturb imprinted methylation maintenance of the (a) Snrpn, (b) Kcnq1ot1, and (c) H19 ICRs in blastocysts. Embryos were derived from spontaneously ovulating females. Diamonds represent the mean methylation levels of maternal (red) or paternal (blue) alleles for the Snrpn, Kcnq1ot1, and H19 ICRs in individual blastocysts (n = 9–22 embryos, n = 3–7 females per age group). Same letter (a), no statistically significant difference between groups

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