Fig. 6From: Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genesGene expression of SKI, GTF2H4, TNXB, and EIF2AK3 and in human donor RPE samples. Relative mRNA quantification of SKI (a), GTF2H4 (b), TNXB (c), and EIF2AK3 (d) using RT-qPCR in AMD (n = 4) compared to normal (n = 3) human donor samples. Significant reduction in SKI (p = 0.0235) (a), GTF2H4 (p = 0.0174) (b), TNXB (p = 0.05) (c), and EIF2AK3 (p = 0.011) (d) was present in AMD (*p ≤ 0.05). All statistical analysis was performed using an unpaired Student’s t testBack to article page