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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Adipose tissue inflammation and VDR expression and methylation in colorectal cancer

Fig. 3

Methylation analyses at specific CpG dinucleotides for VDR and NFκB1 promoters and gene expression of the epigenetic factor DNMT3A were performed to compare both the control and CRC groups. Comparisons of the global VDR methylation (a) and among the CpG dinucleotides analyzed (b) by Mann-Whitney U test. Non-parametric (Mann-Whitney U test) comparison for the global NFκB1 methylation (c) and at specific CpG dinucleotides (d), as well as for the methyltransferase DNMT3A gene expression (e). * means p < 0.05. Vitamin D receptor (VDR), DNA methyltransferase 3a (DNMT3A), colorectal cancer (CRC)

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