Table 2 Methylation status of individual genes and associations with disease-free survival using Cox proportional hazards model in 230 patients
Gene | Methylation status | Overall(%) | Recurrence events | Adjusted RR (95% CI)†| |
|---|---|---|---|---|---|
Positive (N = 91) | Negative (N = 139) | ||||
SST | Yes | 194(84.3) | 78 | 116 | Â |
No | 36(15.7) | 13 | 23 | 0.847 (0.470–1.526) | |
TAC1 | Yes | 146(63.5) | 65 | 81 | Â |
No | 84(36.5) | 26 | 58 | 1.620 (1.018–2.578)* | |
HCRT | Yes | 75(32.6) | 37 | 38 | Â |
No | 155(67.4) | 54 | 101 | 1.235 (0.805–1.895) | |
NPY | Yes | 65(28.3) | 26 | 39 | Â |
No | 165(71.7) | 65 | 100 | 1.126 (0.713–1.779) | |
GAL | Yes | 46(20.0) | 27 | 19 | Â |
No | 184(80.0) | 64 | 120 | 1.692 (1.063–2.694)* | |
MI | 3–5 | 104(45.2) | 53 | 51 |  |
0–2 | 126(54.8) | 38 | 88 | 1.756 (1.160–2.659)* | |