Table 2 Associations of birth weight-for-gestational age (BW/GA) with DNA methylation sitesa in venous umbilical cord blood at delivery, among 476 participants in Project Viva
From: Birth weight-for-gestational age is associated with DNA methylation at birth and in childhood
CpG sitea | Difference in % methylation for 1-unit increment in BW/GA z-score (95% CI) | Nominal p value | Geneb | Gene regionb | chr |
|---|---|---|---|---|---|
cg26663636 | −0.39 (−0.52, −0.25) | 4.31E−09 | NOS1AP | Body | chr1 |
cg18181229 | 1.86 (1.16, 2.56) | 1.80E−07 | PBX1 | Body | chr1 |
cg06750897 | 1.93 (1.22, 2.64) | 1.83E−07 | PBX1 | Body | chr1 |
cg00222472 | 1.78 (1.12, 2.45) | 2.03E−07 | PBX1 | Body | chr1 |
cg20682146 | 1.54 (0.91, 2.17) | 1.60E−06 | PBX1 | Body | chr1 |
cg05780177 | 0.24 (0.14, 0.35) | 2.39E−06 | DENND1B | TSS200 | chr1 |
cg00325458 | 0.1 (0.06, 0.14) | 7.27E−07 | REL | TSS200 | chr2 |
cg23483765 | 0.22 (0.14, 0.31) | 1.15E−07 | NIPAL4 | TSS200 | chr5 |
cg24353833 | 0.42 (0.27, 0.57) | 8.38E−08 | NRM | Body | chr6 |
cg24641186 | 0.46 (0.27, 0.64) | 1.41E−06 | TFAP2B | Body | chr6 |
cg20392842 | −1.58 (−2.24, −0.92) | 2.54E−06 | HLA-DMB | TSS200 | chr6 |
cg09364590 | 0.72 (0.42, 1.03) | 3.66E−06 | TIAM2 | Body;TSS200 | chr6 |
cg21809331 | 0.22 (0.13, 0.31) | 2.28E−06 | RBM28 | TSS200 | chr7 |
cg14731462 | −0.92 (−1.29, −0.55) | 4.20E−07 | PTPRE | 5′UTR | chr10 |
cg25953130 | −2.01 (−2.8, −1.22) | 7.76E−07 | ARID5B | Body | chr10 |
cg23890469 | 0.57 (0.34, 0.81) | 1.55E−06 | MMRN2 | Body | chr10 |
cg25124943 | −0.92 (−1.31, −0.53) | 2.34E−06 | – | – | chr10 |
cg11606444 | 0.68 (0.39, 0.98) | 4.28E−06 | SORL1 | Body | chr11 |
cg01345517 | 0.15 (0.09, 0.21) | 1.55E−06 | DERA | Body | chr12 |
cg06648759 | −1.08 (−1.52, −0.63) | 2.02E−06 | – | – | chr13 |
cg14276580 | −0.94 (−1.33, −0.54) | 2.24E−06 | – | – | chr13 |
cg20549688 | 0.21 (0.13, 0.29) | 3.20E−07 | GTF2A2 | TSS200 | chr15 |
cg21842999 | 0.51 (0.3, 0.72) | 3.20E−06 | SHF | Body | chr15 |
cg09476997 | 1.81 (1.06, 2.57) | 2.20E−06 | SLC9A3R2 | Body; | chr16 |
cg27283514 | 1.51 (0.86, 2.16) | 3.34E−06 | – | – | chr16 |
cg19914554 | 0.73 (0.47, 0.98) | 2.21E−08 | CD7 | 1stExon;5′UTR | chr17 |
cg20186396 | 0.73 (0.45, 1.02) | 3.26E−07 | CD7 | TSS200 | chr17 |
cg14909906 | 0.17 (0.1, 0.25) | 2.37E−06 | KDSR | 1stExon;5′UTR | chr18 |
cg23882285 | 0.12 (0.07, 0.17) | 3.37E−06 | ROCK1 | TSS200 | chr18 |
cg23026246 | 0.13 (0.08, 0.19) | 2.23E−06 | SPTBN4 | Body | chr19 |
cg23877608 | 0.17 (0.1, 0.24) | 2.35E−06 | CCDC114 | TSS200 | chr19 |
cg23344780 | −0.58 (−0.83, −0.33) | 4.10E−06 | EMP3 | 5′UTR | chr19 |
cg04803921 | 0.13 (0.08, 0.19) | 1.68E−06 | HM13 | Body | chr20 |
cg08422803 | 1.05 (0.69, 1.41) | 8.04E−09 | ITGB2 | TSS200;5′UTR | chr21 |