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Table 2 Heart rate (bpm) at age 9 years in relation to ANRIL promoter DNA methylation

From: DNA methylation at birth within the promoter of ANRIL predicts markers of cardiovascular risk at 9 years

CpG Hg19 coordinates β value p value Adjusted p
1 chr9: 21993721 −1.98 0.031 0.041
2 chr9: 21993697 −2.45 0.020 0.033
3 chr9: 21993694 −2.56 0.080 0.103
4 chr9: 21993654 −1.5 0.195 0.168
5 chr9: 21993645 −0.669 0.484 0.488
6 chr9: 21993638 −1.42 0.128 0.196
7 chr9: 21993629 0.096 0.938 0.936
8 chr9: 21993603 −1.18 0.288 0.402
9 chr9: 21993583 −0.626 0.642 0.463
  1. β values represent a 10 % change in methylation. DNA methylation levels were determined via pyrosequencing. Linear regressions were used to compare methylation and heart rate. Adjusted p values are adjusted for age, sex, total fat mass at 8 years and mother smoking during pregnancy