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Table 2 Information on the CpG sites in the selected models before bootstrapping

From: The interplay of DNA methylation over time with Th2 pathway genetic variants on asthma risk and temporal asthma transition

Gene CpG sites MapInfo§ Location Chrom. Mean at age 10 (SD)# Mean at age 18 (SD)# P value$
GATA3 cg12405139 8106035 Body 10 0.93 (0.0008) 0.92 (0.011) 0.12
GATA3 cg13543854 8095477 TSS200; TSS1500 10 0.047 (0.007) 0.042 (0.008) 5.84 × 10−3
IL4R cg09791102 27353414 Body 16 0.94 (0.046) 0.94 (0.050) 0.14
IL4R cg26937798 27326054 5’UTR 16 0.076 (0.022) 0.062 (0.013) 9.14 × 10−6
IL4 cg23943829 13200911 TSS1500 5 0.88 (0.016) 0.86 (0.019) 1.07 × 10−5
  1. §MapInfo refers to “genomic coordinates on the human genome” and it gives genomic location.
  2. #Means and standard deviations (SD) are calculated using beta values. Beta values are used to measure DNA methylation levels of each CpG site.
  3. $P values are from paired t-tests comparing the difference in DNA methylation between ages 10 and 18 years on logit-transformed beta values (to approximate normality).
  4. Mean and SD of DNA methylation of each CpG site are calculated in beta scores.