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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Azithromycin attenuates wheezing after pulmonary inflammation through inhibiting histone H3K27me3 hypermethylation mediated by EZH2

Fig. 6

AZM reduces induced IL-10 expression caused by LPS through inhibiting H3K27me3 hypermethylation. A Western blot and quantification of the expression levels of TLR4, NF-κB P65 and NF-κB p-P65 in rat alveolar macrophages (NR8383). B Western blotting and quantification of EZH2, p-EZH2, H3K27me3 in the NR8383 cells. C Western blotting and quantification of the expression levels of IL-10 in the NR8383 cells. #P < 0.05 versus the Control group, *P < 0.05 versus the LPS group (n = 3)

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Clinical Epigenetics

ISSN: 1868-7083

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