Fig. 2From: Genome-wide assessment of DNA methylation alterations induced by superovulation, sexual immaturity and in vitro follicle growth in mouse blastocystsDNA methylation differences in mouse blastocysts from natural ovulation and superovulation adult conditions. a Scatterplot showing correlation between methylation levels of individual 100-CpG tiles common to all datasets (n = 206,059) in mouse blastocysts of the indicated two conditions, using data merged for the 4 samples per group. Differentially methylated tiles were determined by logistic regression analysis in SeqMonk (p < 0.05 corrected for multiple comparisons using Benjamini–Hochberg, methylation difference ≥ 10%). Red and blue indicate differentially methylated tiles that are hypermethylated or hypomethylated, respectively, in the NO group. b Heatmap showing the 100-CpG differentially methylated tiles identified between NO and SOa groups (n = 401). c Beanplots indicating methylation levels in blastocysts of the CGIs identified as methylated in MII oocytes (n = 1226); within each beanplot, boxplot shows median value and 25–75th percentiles and whiskers show the lowest and highest observation. d Heatmap showing the 13 differentially methylated CGIs identified between NO and SOa groups and the overlapping genes. CGI promoters are indicated in bold. NO, natural ovulation; SOa, superovulation adult; CGI, CpG islandBack to article page