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Table 3 Differentially methylated regions (DMR) in PPAT of obese/overweight PCa patients compared to normal weight controls

From: Epigenome-wide DNA methylation profiling of periprostatic adipose tissue in prostate cancer patients with excess adiposity—a pilot study

DMR Chr Start–end (bp) Size (bp) P value FDR Located gene DMCs* Relation to CpG island
1 6 30,038,791–30,039,801 1010 5.11E−05 2.07E−02 RNF39 37(0) Island
2 6 29,648,161–29,649,084 923 1.54E−03 2.08E−01 ZFP57# 22(0) Open sea
3 17 71,228,123–71,228,832 709 3.10E−03 2.86E−01 FAM104A 4(3) Island
4 17 71,228,123–71,228,832 709 3.10E−03 2.86E−01 C17orf80 10(8) Island
5 12 42,720,006–42,720,167 161 5.56E−03 2.86E−01 PPHLN1 4(0) Island
6 6 31,650,735–31,651,158 423 5.59E−03 2.86E−01 MIR4646# 16(0) Island
7 7 27,169,674–27,170,961 1287 5.66E−03 2.86E−01 HOXA4 17(11) Island
8 6 33,282,736–33,283,145 409 5.87E−03 2.86E−01 TAPBP 18(18) Island
9 20 57,463,763–57,464,129 366 6.74E−03 2.86E−01 GNAS 15(0) Island
10 16 86,546,938–86,547,322 384 7.03E−03 2.86E−01 FOXF1 4(0) Shore
  1. #The DMR is located at the intergenic region
  2. Chr chromosome
  3. *The number in the bracket is the quantities of DMCs located at the promoter (TSS200 and TSS1500) regions