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Table 1 Descriptive characteristics of study participants in Project Viva with information on DNA methylation and mid-childhood IgE

From: Epigenome-wide association study of total serum immunoglobulin E in children: a life course approach

Participant characteristics

Cord blood DNA methylation data (N = 242)

Mid-childhood DNA methylation data (N = 411)

DNA methylation data at both time points (N = 217)

Maternal characteristics

Age (years), mean ± SD

32.0 (5.6)

32.3 (5.5)

32.3 (5.4)

Smoking status, N (%)

 Smoked during pregnancy

24 (10%)

41 (10%)

20 (9%)

 Former smoker

53 (22%)

83 (20%)

49 (23%)

 Never smoker

165 (68%)

287 (70%)

148 (68%)

College graduate, N (%)

 Yes

158 (65%)

271 (66%)*

144 (66%)

 No

84 (35%)

138 (34%)

73 (34%)

Atopy history

 Yes

90 (37%)

163 (40%)*

80 (37%)

 No

152 (63%)

246 (60%)

137 (63%)

Child characteristics

Gestational age (weeks), mean ± SD

39.7 (1.6)

39.6 (1.6)

39.7 (1.6)

Age at blood drawn (years), mean ± SD

7.8 (0.7)†

7.8 (0.7)†

7.8 (0.7)

Sex, N (%)

   

 Female

117 (48%)

201 (49%)

105 (48%)

 Male

125 (52%)

210 (51%)

112 (52%)

Race/ethnicity, N (%)

 White

161 (67%)

256 (62%)†

143 (66%)

 Black

42 (17%)

77 (19%)

39 (18%)

 Other

39 (16%)

77 (19%)

35 (16%)

Total serum IgE level in mid-childhood, (kU/L)

146.4 (310.2)

152.1 (286.2)

142.5 (311.0)

  1. *Number of missing = 2
  2. †Number of missings = 1