Skip to main content

Table 2 Univariate and multivariate analyses of prognostic factors for complete remission in whole-cohort and non-APL-AML patients

From: H19 overexpression promotes leukemogenesis and predicts unfavorable prognosis in acute myeloid leukemia

 

Univariate analysis

Multivariate analysis

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

Whole-cohort AML

Age

0.119 (0.054–0.262)

< 0.001

0.162 (0.069–0.379)

< 0.001

WBC

0.269 (0.126–0.575)

0.001

0.505 (0.204–1.253)

0.140

Karyotype classifications

0.214 (0.112–0.408)

< 0.001

0.269 (0.139–0.519)

< 0.001

H19 expression

0.370 (0.189–0.726)

0.004

0.416 (0.185–0.935)

0.034

Non-APL AML

Age

0.164 (0.069–0.392)

< 0.001

0.199 (0.079–0.502)

0.001

WBC

0.353 (0.153–0.819)

0.015

0.522 (0.198–1.378)

0.189

Karyotype classifications

0.316 (0.145–0.691)

0.004

0.297 (0.129–0.687)

0.005

H19 expression

0.361 (0.164–0.791)

0.011

0.306 (0.123–0.762)

0.011

  1. Variables were composed of age (≤ 60 vs. > 60 years), WBC (≥ 30 × 109 vs. < 30 × 109/L), karyotype classifications (favorable vs. intermediate vs. poor), and H19 expression (low vs. high). The multivariate analysis included variables with P < 0.100 in univariate analysis for complete remission
  2. AML acute myeloid leukemia, APL acute promyelocytic leukemia, WBC white blood cells, CI confidence interval
Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us