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Fig. 3 | Clinical Epigenetics

Fig. 3

From: H19 overexpression promotes leukemogenesis and predicts unfavorable prognosis in acute myeloid leukemia

Fig. 3

Prognostic value of H19 expression on overall survival in AML using TCGA and GEO data. ac The impact of H19 expression on overall survival (OS) in a cohort of 200 AML patients from The Cancer Genome Atlas (TCGA) databases. The patients were classified into H19 low-expressed and high-expressed groups by the median level of ID4 expression. a OS among whole-cohort AML. b OS among non-APL-AML. c OS among cytogenetically normal AML (CN-AML). dg The impact of H19 expression on OS in two independent cohorts of 78 and 162 CN-AML patients were obtained from Gene Expression Omnibus (GEO) data. Survival analysis was performed through the online web tool Genomicscape. d Probe 224646_at among a cohort of 78 CN-AML patients. e Probe 224997_at among a cohort of 78 CN-AML patients. f Probe 224646_at a cohort of 162 CN-AML patients. g Probe 224997_at among a cohort of 162 CN-AML patients

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