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Table 2 iPLEX MassArray verification of the seven identified DMRs in the independent birth cohort FLEHS2

From: GLI2 promoter hypermethylation in saliva of children with a respiratory allergy

Gene

FLEHS2 iPLEX MassArray data

Allergy

Control

Delta beta

p a

Beta ± SD

Beta ± SD

ALOX12

0.24 ± 0.05

0.26 ± 0.06

− 0.016

0.443

APOBEC1

0.79 ± 0.17

0.82 ± 0.16

− 0.036

0.348

GLI2

0.72 ± 0.08

0.65 ± 0.10

0.071

0.017*

GRAMD1B

0.08 ± 0.03

0.10 ± 0.03

− 0.020

0.035*

HTRA3

0.59 ± 0.08

0.55 ± 0.06

0.041

0.057

MED24

0.37 ± 0.04

0.39 ± 0.04

− 0.016

0.207

OPCML

0.47 ± 0.08

0.50 ± 0.10

− 0.030

0.317

  1. aCorrected for gender
  2. Genes given in bold are significantly differentially methylated (*p <0.05)
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Clinical Epigenetics

ISSN: 1868-7083

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