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Table 1 Baseline characteristics of HyperGen study participants

From: Epigenome-wide association study of metabolic syndrome in African-American adults

 

MetS+ (N = 284)

MetS− (N = 330)

p value*

Age†

52.0 ± 10.0

46.0 ± 11.0

< 0.0001

High WC/obesity

 WC (cm)†

112.4 ± 16.6

96.6 ± 16.9

< 0.0001

 BMI†

35.4 ± 8.1

29.8 ± 7.4

< 0.0001

Elevated triglycerides

 Triglycerides (mg/dL)§

125.5 ± 83.5

77.0 ± 42.8

< 0.0001

Reduced HDL cholesterol

 HDL cholesterol (mg/dL)†

46.9 ± 12.5

58.8 ± 15.5

< 0.0001

Elevated blood pressure

 DBP (mmHg)†

75.3 ± 11.8

75.5 ± 13.3

0.8

 SBP (mmHg)†

136 ± 22.8

127.6 ± 23.7

< 0.0001

 Hypertension (%)

86.6

48.9

< 0.0001

Elevated fasting glucose

 Fasting glucose (mg/dL)†

133.8 ± 69.9

94.2 ± 31.2

< 0.0001

Metabolic components** (%)

 0

0

17.3

 

 1

0

33.9

 

 2

0

48.8

 

 3

51.4

0

 

 4

28.2

0

 

 5

20.4

0

 
  1. BMI body mass index, HDL high-density lipoprotein, LDL low-density lipoprotein, DBP diastolic blood pressure, SBP systolic blood pressure
  2. †Presented as mean (standard deviation) for normal continuous characteristics
  3. §Presented as median (interquartile range) for non-parametric continuous characteristics
  4. *Significance determined using chi-square test for categorical, t test for continuous, or kruskal.test test for non-parametric continuous variables
  5. **Metabolic components are high waist circumference (WC), elevated triglycerides, reduced HDL cholesterol, elevated blood pressure, and elevated fasting glucose
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Clinical Epigenetics

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