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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC

Fig. 2

Ranger in discovery (a) or validation (b) in adenocarcinomas. Weighted random forest (Ranger, where confounders like age, gender, smoking status, and stage are adjusted with given 100% weight) was employed in discovery phase (a) and validation set (b) to evaluate the importance of variables. Ranger provides VIS (variable importance score) for each methylation sites. Variables that were in top 5% (red lollipop) or top 10% (yellow lollipop, a flexible criterion) in both discovery phase (a) and validation (b) would be carried forward

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