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Table 3 Association between mgmiRs and clinicopathological characteristics in HNSCC tissues

From: Methylated genomic loci encoding microRNA as a biomarker panel in tissue and saliva for head and neck squamous cell carcinoma

  mgmiR9-1 %(n) mgmiR124-1 %(n) mgmiR124-2 %(n) mgmiR124-3 %(n) mgmiR129-2 %(n) mgmiR137 %(n) mgmiR148a %(n) Combined mgmiRs %(n)
Location
 OSCC (95) 66.3(63) 72.6(69) 71.6(68) 52.6(50) 73.7(70) 64.2(61) 43.2(41) 92.6(88)
 OPSCC (44) 75(33) 72.7(32) 86.4(38) 50(22) 79.6(35) 61.4(27) 40.9(18) 97.7(43)
 LSCC (48) 56.3(27) 68.8(33) 81.3(39) 43.8(21) 68.8(33) 58.3(28) 50.0(24) 89.6(43)
Smoking
 Never (37) 70.3(26) 67.6(25) 73.0(27) 56.8(21) 64.9(24) 59.5(22) 51.4(19) 89.2(33)
 Current (50) 74.0(37) 76.0(38) 86.0(43) 44.0(22) 74.0(37) 64.0(32) 36.0(18) 96.0(48)
 Ex (78) 64.1(50) 75.6(59) 73.1(57) 53.9(42) 78.2(61) 68.0(53) 46.2(36) 96.2(75)
HPV
 Positive (25) 68.0(17) 68.0(17) 88(22) 72(18) 84.0(21) 52.0(13) 48.0(12) 96(24)
 Negative (41) 51.2(21) 63.4(26) 65.9(27)* 53.7(22) 56.1(23)* 61.0(25) 39.0(16) 80.5(33)*
Tumor size
 T1 (46) 76.0(35) 69.6(32) 65.2(30) 56.5(26) 56.5(26) 63.0(29) 34.8(16) 93.5(43)
 T2 (49) 65.3(32) 77.6(38) 87.8(43) 51.0(25) 83.7(41) 65.3(32) 53.1(26) 95.9(47)
 T3 (41) 58.5(24) 58.5(24) 75.6(31) 39.0(16) 70.7(29) 48.8(20) 36.6(15) 87.8(36)
 T4 (50) 62.0(31) 78.0(39) 80.0(40) 52.0(26) 82.0(41) 68.0(34) 50.0(25) 94.0(47)
Node status
 N0 (78) 69.2(54) 79.5(62)* 76.9(60) 56.4(44) 69.2(54) 60.3(47) 42.3(33) 94.9(74)
 N+ (108) 63.0(68) 65.7(71) 77.8(84) 45.4(49) 76.9(83) 63.0(68) 45.4(49) 91.7(99)
Stage
 I (34) 73.5(25) 73.5(25) 64.7(22) 55.9(19) 55.9(19) 58.8(20) 32.4(11) 91.2(31)
 II (20) 55.0(11) 80.0(16) 85.0(17) 55.0(11) 80.0(16) 75.0(15) 55.0(11) 95.0(19)
 III (59) 67.8(40) 66.1(39) 74.6(44) 44.7(24) 72.9(43) 59.3(35) 37.3(22) 91.5(54)
 IV (73) 63.0(46) 72.6(53) 83.6(61) 53.4(39) 80.8(59) 61.6(45) 52.1(38) 94.5(69)
  1. *p < 0.05