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Table 2 Selected DMRs at the trained state. DMRs which are found to be responsive to exercise and whose nearest gene has been found to escape epigenetic reprogramming, Chr is chromosome, Difference is the median of methylation differences observed within the cluster, upon exercise training

From: Endurance training remodels sperm-borne small RNA expression and methylation at neurological gene hotspots

Chr

Start

End

Difference

Distance to TSS

Gene Symbol

Description

chr3

196,260,561

196,260,561

− 5.3%

− 18,324

SMCO1

Single-pass membrane protein with coiled-coil domains 1

chr4

132,671,876

132,671,876

2.8%

− 1,398,594

PCDH10

Protocadherin 10

chr4

152,283,426

152,283,475

− 15.8%

− 46,923

FAM160A1

Family with sequence similarity 160 member A1

chr4

189,100,182

189,100,182

− 30.9%

35,385

TRIML1

Tripartite motif family like 1

chr9

133,616,767

133,616,767

− 13.0%

27,499

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

chr9

135,127,959

135,128,001

− 47.2%

77,885

SETX

Senataxin

chrY

9,384,788

9,384,795

12.8%

19,299

TSPY3

Testis specific protein, Y-linked 3