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Table 4 The relationship between clinicopathological characteristic of three groups and HPV integrations

From: Identification of reliable biomarkers of human papillomavirus 16 methylation in cervical lesions based on integration status using high-resolution melting analysis

Variable No. of patients HPV integrations P value
Negative Positive
No. % No. %
SCC patients
 Age
  < 40 6 0 0 6 100 0.99
  40–50 32 2 6.25 30 93.8
  > 50 12 1 8.33 11 91.7
 Stage
  Stage I 13 0 0 13 100 0.558
  Stage II+ 37 3 8.1 34 91.9
 Metastasis
  Negative 42 2 4.76 40 95.2 0.414
  Positive 8 1 12.5 7 87.5
 Number of pregnancies
  < 3 21 1 4.76 20 95.2 0.99
  ≥ 3 25 2 8 23 92
 Number of abortions
  < 2 22 3 13.6 19 86.3 0.079
  ≥ 2 28 0 0 28 100
HSIL and LSIL patients
 HSIL 30 4 13.3 26 86.7 0.017
 LSIL 35 14 40 0.6 60
 Age
  < 40 52 7 13.5 45 86.5 0.19
  40–50 11 4 36.4 7 63.6
  > 50 2 0 0 2 100
  1. This table shows both the clinicopathological characteristic of SCC, HSIL, and LSIL and their frequency of HPV integrations. P < 0.05 is considered to be significantly different