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Fig. 6 | Clinical Epigenetics

Fig. 6

From: DNA methylation alterations in iPSC- and hESC-derived neurons: potential implications for neurological disease modeling

Fig. 6

Single gene DNA methylation analysis. a-e DNA methylation levels (%) of individual CpGs of single genes from isogenic hESC-derived and iPSC-derived NSC and neurons (APP, GNAS, MIR886, PMP22, SNCA intron 1). The % difference at each CpG between hESC-derived and iPSC-derived neurons is depicted at the secondary x-axis. Neurons were differentiated for 6 weeks. Blue = hESC-derived NSC or neurons; red = iPSC-derived NSC or neurons

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