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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Genome-wide DNA methylation profiling integrated with gene expression profiling identifies PAX9 as a novel prognostic marker in chronic lymphocytic leukemia

Fig. 3

Supervised hierarchical clustering of hypermethylated-dowregulated and hypomethylated -upregulated genes selected on the basis of significant log2FC values in IGHV mutated (n = 05) Vs. IGHV unmutated (n = 09) CLL. The Euclidean hierarchical clustering was performed using Gene Spring Gx software version 13.5 and is based on normalized intensity values. Each row represents an individual patient and each column represents a gene. A gradient color scale ranging between blue (hypermethylated and downregulated) and red (hypomethylated and upregulated) is included

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