Table 4 Validated gene targets of hsa-miR-451a & hsa-miR-663a and GO Biological Processes Key Words
From: Pulmonary microRNA profiling: implications in upper lobe predominant lung disease
Gene ID | Name | GO Biological Process Key Words |
|---|---|---|
miR-451a gene targets | ||
 MIF | (Macrophage migration inhibitory factor) | Immunity, inflammatory response, innate immunity |
 BCL2 | (B cell lymphoma 2) | apoptosis |
 CAB39 | (calcium binding protein 39) | cell cycle arrest |
 ABCB1 | (Multidrug resistance protein 1) | transport |
 AKT1 | (RAC-alpha serine/threonine-protein kinase) | apoptosis |
 MMP-2 | (Matrix metalloproteinase 2) | angiogenesis, collagen degradation |
 MMP-9 | (Matrix metalloproteinase 9) | collagen degradation |
 RAB14 | (RAS-related protein Rab-14) | protein transport, transport |
 RAB5A | (RAS-related protein Rab-5A) | endocytosis, phagocytosis |
 IL6R | (IL6 Receptor) | cytokine mediated signaling pathway |
miR-663a gene targets | ||
 JUNB | (jun B proto-oncogene) | transcription, transcriptional regulation |
 JUND | (jun D proto-oncogene) | transcription, transcriptional regulation |
 KLF4 | (Kruppel-like factor 4) | transcription, transcriptional regulation |
 FOSB | (FBJ murine osteosarcoma viral oncogene) | transcription regulation (AP1) |
 SLC7A5 | (solute carrier family 7, member 5) | amino acid transport (lung) |
 NAV2 | (neuron navigator 2) | helicase, hydrolase |
 CEBPB | (CCAAT/enhancer binding protein, beta) | transcription, transcriptional regulation |
 HSPG2 | (heparin sulfate proteoglycan 2-perecan) | angiogenesis, (basement membrane) |
 CDK1 | (cyclin-dependent kinase 1) | apoptosis, cell cycle & division, mitosis |
 TGFB | (transforming growth factor beta) | inflammatory response |