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Table 3 Association analysis for SNPs and DNAm sites located in ZFHX3 and SMARCA4 for the control group

From: Epigenome-wide association of myocardial infarction with DNA methylation sites at loci related to cardiovascular disease

SNP Chromosome Position (bp) Strand Allele (minor/major) MAF (%) DNAm site Effect ± SE p
ZFHX3
 rs7193343 16 73,029,160 + C/T 40.4 cg07786668 −0.0011 ± 0.0011 0.307
       cg00614832 0.0004 ± 0.0013 0.755
 rs2106261 16 73,051,620 + T/C 33.1 cg07786668 −0.0016 ± 0.0011 0.176
       cg00614832 0.0004 ± 0.0014 0.774
 rs879324 16 73,068,678 + A/G 38.3 cg07786668 −0.0015 ± 0.0011 0.186
       cg00614832 0.0005 ± 0.0014 0.718
SMARCA4
 rs3786725a 19 11,166,827 + A/G 11.2 cg17218495 0.0008 ± 0.0011 0.461
  1. The Effect and p values were calculated with a GLM. The Effect value represents the change in β-value per minor allele copy for the SNP
  2. aThis SNP is in linkage disequilibrium with rs1122608 in SMARCA4 (r 2 = 0.956 based on Asian samples of the 1000 Genomes Project phase I)