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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas

Fig. 4

Methylation (a) and expression levels (b) confirmation of the selected genes. a ERBB3, FGF1, GABRB2, HMGA2, and RDH5 hypomethylation and FGFR2 hypermethylation were confirmed in PTC samples by pyrosequencing after DNA modification by bisulfite. b. ERBB3, FGF1, GABRB2, HMGA2, and RDH5 overexpression and FGFR2 downexpression were confirmed in PTC by RT-qPCR. The boxplot indicates the interquartile range and median. ***p < 0.001 by comparing PTC to NT (Student’s t test)

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