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Table 3 Adjusted associations for LEP methylation in boys with overweight and obese status as primary predictor

From: Associations of LEP, CRH, ICAM-1, and LINE-1 methylation, measured in saliva, with waist circumference, body mass index, and percent body fat in mid-childhood

Obesity status (predictors)

LEP methylation in boys (dependent variable)

CpG-1

β (SE)

CpG-2

β (SE)

CpG-3

β (SE)

CpG-4

β (SE)

Mean

β (SE)

Overweight

0.373 (1.140)

0.730 (0.495)

0.850 (0.719)

1.207 (1.243)

0.790 (0.768)

Obese

−2.822** (0.993)

−1.507*** (0.432)

−2.149*** (0.627)

−3.961*** (1.080)

−2.610*** (0.666)

  1. Models adjusted for age and parental BMI
  2. P values: ***P < 0.001; **0.001 ≤ P < 0.01; *0.01 ≤ P < 0.0