Skip to main content

Table 1 Anthropometrical and metabolic characteristics of the family population

From: DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance

 

Men (n = 51)

Women (n = 86)

P value

Age (years)

53.8 ± 12.0

53.9 ± 10.7

1.0

Weight (kg)

90.7 ± 16.8

76.3 ± 15.9

<0.0001

Height (cm)

177.2 ± 7.9

165.8 ± 6.4

<0.0001

BMI (kg/m2)

28.8 ± 3.8

27.90 ± 6.0

0.4

Glucose tolerance status

 NGT (normal glucose tolerance)

26 (51 %)

61 (71 %)

 

 IFG (impaired fasting glucose)

3 (6 %)

4 (5 %)

 

 IGT (impaired glucose tolerance)

10 (20 %)

7 (8 %)

 

 T2D (type 2 diabetes mellitus)

12 (24 %)

14 (16 %)

 

Fasting glucose (mmol/l)

6.9 ± 3.0

6.0 ± 2.1

0.02

Fasting insulin (pmol/l)

54.3 ± 35.5

46.2 ± 41.0

0.05

HbA1c (%)

5.8 ± 1.3

5.7 ± 1.0

0.6

Whole-body insulin sensitivity

6.27 ± 4.06

8.73 ± 5.29

0.007

  1. All values are means ± SD. Fasting glucose, fasting insulin, and HbA1c values were logarithmically transformed to obtain normal distribution prior to analysis. P values were calculated in R 3.1.0 using a mixed linear model with family number as a random factor and sex, age, and BMI as a fixed factor. Glucose tolerance status: numbers (and percentage) of NGT, IFG, IGT, and T2D individuals