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Table 1 Details of SPMS and healthy control individuals

From: Next-generation sequencing reveals broad down-regulation of microRNAs in secondary progressive multiple sclerosis CD4+ T cells

  Next generation sequencing Replication cohort
SPMS HC SPMS HC
Number 12 12 12 10
Female 9 9 8 5
Age in years (mean ± SD) 60.2 ± 8.3 61.3 ± 9.5 61.4.0 ± 6.5 60.1 ± 5.9
EDSS (mean ± SD) 6.9 ± 0.9 NA 5.9 ± 1.0 NA
Active SPMS 3 NA 4 NA
Disease duration in years (mean ± SD) 25.6 ± 11.1 NA 18.3 ± 6.5 NA
Progression duration (mean ± SD) 10.8 ± 8.1 NA 8.9 ± 6.2 NA
  1. EDSS expanded disability status scale, SD standard deviation, NA not applicable