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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Histone modification signature at myeloperoxidase and proteinase 3 in patients with anti-neutrophil cytoplasmic autoantibody-associated vasculitis

Fig. 1

Bioinformatic analysis of microarray gene expression data comparing leukocytes from AAV patients to healthy controls. a Principal component analysis of the gene expression profile is shown for AAV patients, represented by red dots, and for healthy controls, represented by blue dots. b Gene expression data was processed with Ingenuity Pathway Analysis software to unveil biological networks. The primary network shown is for genes with functional annotations related to histone, histone H3, and/or histone H4. Genes with increased or decreased expression in AAV patients compared to healthy controls are shown in red and green, respectively

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