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Table 5 Expression of CBX2-regulated genes involved in mitosis following CBX2 silencing

From: Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer

Gene Fold change p value Gene Fold change p value
CENP family SMC family
CENPA −3.1 2.1E-03 SMC1 −2.0 3.3E-02
CENPE −3.0 1.6E-04 SMC2 −2.7 1.4E-04
CENPH −2.9 4.4E-03 SMC3 −1.3 3.4E-03
CENPI −3.0 1.7E-03 SMC4 −2.9 1.1E-03
CENPK −2.4 1.0E-03 SMC6 −1.5 3.0E-03
CENPL −1.8 5.6E-03 Mitotic signaling proteins
CENPN −1.9 1.1E-04 AURKA −2.6 3.7E-04
CENPO −2.4 4.2E-03 AURKB −3.4 1.3E-03
CENPP −1.6 2.4E-02 CCNB1 −2.4 5.0E-04
CENPQ −1.8 1.1E-03 KI67 −2.0 1.2E-04
CENPW −2.8 1.1E-03 CDK1 −2.3 2.2E-04
SKA family CDC25A 2.2 6.7E-04
SKA1 −3.0 1.4E-04 PLK1 −2.7 1.0E-02
SKA2 −2.1 4.9E-03 PLK3 −1.4 4.8E-05
SKA3 −2.8 3.5E-05 PLK4 −2.9 1.5E-03