Fig. 5From: Genome-wide DNA methylation analysis of pseudohypoparathyroidism patients with GNAS imprinting defectsHeatmap showing methylation of known imprinted genes in PHP patients. Methylation values of the genes are extracted from data obtained with the HM450k. Dark green and red respresent −3SD and +3SD, respectively, of the mean as determined in 20 controls. Lighter green and red represent additional cut-offs for absolute methylation <0.20 and >0.80. Patients* have multi-locus methylation abnormalities. PHP ΔSTX16 patients with underlying STX16 deletionBack to article page