Skip to main content

Advertisement

Fig. 1 | Clinical Epigenetics

Fig. 1

From: Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairs

Fig. 1

Diagnostic characteristics and global methylation profiles of 41 cancer-discordant MZ twin-pairs. a Number of cases for each primary location of cancer, where a blood sample was obtained before (white) and after (black) cancer diagnosis. b Dendrogram of the unadjusted global methylation profiles. Annotation bars denote each individual’s cancer status, type of cancer (identical for both twins in a pair), and family identifier (identical for both twins in a pair). c Pair-wise correlation in DNA methylation profiles shows greater similarity within MZ pairs, compared to pairs of unrelated individuals, either paired at random or at within affection status

Back to article page