Fig. 3From: Imprinting disorders: a group of congenital disorders with overlapping patterns of molecular changes affecting imprinted lociThe 11p15.5 cluster can be divided in two functional domains whose imprinting is dependent on distinct imprinting control regions (H19/IGF2: IG DMR and KCNQ1OT1: TSS DMR). Mainly hypomethylation of the KCNQ1OT1: TSS DMR is responsible for SRSBack to article page