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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Imprinting disorders: a group of congenital disorders with overlapping patterns of molecular changes affecting imprinted loci

Fig. 1

PLAGL1 imprinted region on chromosome 6q24, altered in TNDM. The currently known imprinted loci associated with one of the known IDs. (Filled boxes, protein coding genes; empty boxes, non-coding genes; Ω miRNAs; filled lollipops, methylated regions; empty lollipops, unmethylated regions; black, genes with biparental expression; red, genes expressed from the maternal (mat) chromosome; blue, genes expressed from the paternal (pat) chromosome; grey, silenced gene copies. Arrows above the genes, transcription direction of sense genes; arrows below the genes, transcription direction of anti-sense genes. IC, imprinting control region)

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