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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Transgelin gene is frequently downregulated by promoter DNA hypermethylation in breast cancer

Fig. 1

Analyses of AZA affected genes in BC cell lines. a The outline of the gene selection process. The numbers on the left and right represent the probe sets obtained after the filtering process for gene selection in MCF7 and MDA-MB-231 cell lines, respectively. b Number of probe sets significantly up/downregulated by AZA treatment, determined by the selection process given in (a). c, d DAVID analyses of Pathways affected upon AZA treatment in MCF7 cells (c) and MDA-MB 231 cells (d). Bars represent the percentage of up- and downregulated genes involved in the indicated pathways while the lines represent the P values for enrichment. Dashed lines indicate P = 0.05 thresholds

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