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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Whole-genome bisulfite sequencing of cell-free DNA identifies signature associated with metastatic breast cancer

Fig. 3

a Circos plot graphing methylation state for each locus in the CpG island of 21 target genes. The hotspot region exists within each island. The inner circle (red) is MBC, middle circle is DFS (green), and outer circle is H (blue). Hypermethylation is evident in MBC for the target genes. b Vertical scatter plot showing all DML within target CPGIs for MBC versus DFS and H, respectively. Each point represents a CpG locus. Points plotted on the x-axis display the DMVs

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