Fig. 4

DNAm changes in nRBCs, T cells, and monocytes with FACS strategy at their top DM sites. Density distributions of DNAm (β values) at DM CpG sites (FDR <5 %, |Δβ| >0.20) for each of the three cell types, comparing the two sorting methods. DM sites were identified using data from samples sorted by the stringent protocol only. The β distributions suggest that nRBCs are most affected by the sorting protocol. a 8982 nRBC DM sites. b 12,014 CD4 T cell DM sites. c 5940 monocyte DM sites