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Table 4 Pathological characteristics of IDC cases, according to menopausal status

From: Breast cancer risk and imprinting methylation in blood

Characteristic All cases (n = 189) Pre-menopausal (n = 66) Post-menopausal (n = 123)
Grade
 Grade 1 23 (12.2 %) 6 (9 %) 17 (13.8 %)
 Grade 2 84 (44.4 %) 30 (45.5 %) 54 (43.9 %)
 Grade 3 81 (42.9 %) 30 (45.5 %) 51 (41.5 %)
 Missing info. 1 (0.5 %) 1 (0.8 %)
Lymph node involvement
 None 119 (63 %) 38 (57.6 %) 81 (65.9 %)
 Axillary lymph nodes 69 (36.5 %) 28 (42.4 %) 41 (33.3 %)
 Missing info. 1 (0.5 %) 1 (0.8 %)
Hormone receptor status
 ER positive 146 (77.2 %) 54 (81.8 %) 92 (74.8 %)
 ER negative 43 (22.8 %) 12 (18.2 %) 31 (25.2 %)
 PR positive 145 (76.7 %) 53 (80.3 %) 92 (74.8 %)
 PR negative 44 (23.3 %) 13 (19.7 %) 31 (25.2 %)
HER2 receptor status
 Positive 22 (11.6 %) 11 (16.7 %) 11 (9 %)
 Negative 164 (86.8 %) 54 (81.8 %) 110 (89.4 %)
 Missing info. 3 (1.6 %) 1 (1.5 %) 2 (1.6 %)
Nottingham prognostic index (NPI)
 Good (NPI ≤ 3.4) 71 (37.6 %) 20 (30.3 %) 51 (41.5 %)
 Moderate (NPI 3.41–5.4) 74 (39.1 %) 32 (48.5 %) 42 (34.2 %)
 Poor (NPI > 5.41) 35 (18.5 %) 9 (13.6 %) 26 (21.1 %)
 Missing info. 9 (4.8 %) 5 (7.6 %) 4 (3.2 %)
  1. Participant numbers for pathological characteristics of IDC (invasive ductal carcinoma) patients overall and according to menopausal status (and percent—% of each characteristic)
  2. ER oestrogen receptor, PR progesterone receptor, HER2 human epidermal growth receptor 2