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Table 1 Sensitivity and specificity of markers in DNAs from NPC samples (n = 44) and non-cancerous controls (n = 18) from Morocco using MSP

From: Detection of nasopharyngeal carcinoma in Morocco (North Africa) using a multiplex methylation-specific PCR biomarker assay

Marker gene

Sensitivity %a

Specificity %b

EBNA1

82 (36/44)

94 (17/18)

U-LMP1

59 (26/44)

94 (17/18)

M-RASSF1A

66 (29/44)

94 (17/18)

M-DAPK

25 (11/44)

72 (13/18)

M-ITGA9

50 (22/44)

100 (18/18)

M-P16

45 (20/44)

100 (18/18)

M-WNT7A

69 (11/16)

80 (4/5)

M-CHFR

40 (16/40)

67 (4/6)

M-CYB5R2

47 (17/36)

75 (6/8)

M-WIF1

100 (10/10)

25 (2/8)

M-RIZ1

0 (0/4)

100 (3/3)

M-FSTL1

57 (4/7)

67 (6/9)

  1. aSensitivity = number of positive cases in NPC patients/total number of NPC cases tested
  2. bSpecificity = (total number of tested non-cancerous controls − number of positive cases in tested non-cancerous controls)/total number of tested non-cancerous controls
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Clinical Epigenetics

ISSN: 1868-7083

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